Comparative analysis of cholesterol and hemoglobin levels in dewormed and non-dewormed school-age children
DOI:
https://doi.org/10.35816/jiksh.v14i2.291Keywords:
Anemia, Cholesterol, Deworming, Hemoglobin, School-Age ChildrenAbstract
Introduction: Helminth infections continue to be a significant public health concern among school-age children, particularly in areas with inadequate sanitation. Chronic helminthiasis can impair nutrient absorption, disrupt lipid metabolism, and contribute to anemia. Regular deworming is recommended as a preventive strategy, yet evidence regarding its biochemical impact on cholesterol and hemoglobin levels remains limited. This study aimed to compare cholesterol and hemoglobin levels between dewormed and non-dewormed school-age children.
Methods: A comparative descriptive design was employed involving 30 school-age children, consisting of 15 who routinely consumed deworming medication and 15 who did not. Blood samples were collected by trained health personnel and analyzed in a clinical laboratory. Hemoglobin levels were measured using a photometric method, while total cholesterol levels were determined using an enzymatic method. Descriptive analysis was used to compare mean values between groups.
Results: Children who routinely consumed deworming medication showed lower mean cholesterol levels (152.9 mg/dL) compared with the control group (169.7 mg/dL). Mean hemoglobin levels were also higher in the dewormed group (12.31 g/dL) than in the non-dewormed group (11.86 g/dL). Although not all children fell within the normal reference ranges, the dewormed group demonstrated more stable biochemical profiles overall. These findings suggest that regular deworming may support healthier lipid metabolism and maintain hemoglobin levels within acceptable limits.
Conclusion: The results suggest that periodic deworming has a positive impact on the biochemical status of school-age children. A reduced helminth burden may improve nutrient absorption, stabilize lipid profiles, and prevent chronic blood loss, which can lead to anemia. However, variations between individuals highlight the role of external factors such as diet, sanitation, and reinfection risk. Regular deworming appears to promote better cholesterol and hemoglobin profiles among school-age children, underscoring its importance in child health programs.
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Akib, A. and Rukinah, R. (2024) ‘Effect of anemia in pregnant women on the incidence of premature labor and low birth weight’, Jurnal Ilmiah Kesehatan Sandi Husada, 13(2), pp. 427–433. doi: https://doi.org/10.35816/jiskh.v13i2.1241.
Almeida, I. L. de L. et al. (2022) ‘Social isolation and its impact on child and adolescent development: a systematic review’, Revista Paulista de Pediatria, 40. doi: https://doi.org/10.1590/1984-0462/2022/40/2020385.
Anwar, C. et al. (2018) ‘The Relationship Between Soil Transmitted Helminthes (STH) Infection and Nutritional Status in Students of State Elementary School Number (SDN) 200 Palembang Indonesia’, Bioscientia Medicina : Journal of Biomedicine and Translational Research, 2(2), pp. 42–53. doi: https://doi.org/10.32539/bsm.v2i2.39.
Chauhan, A. et al. (2025) ‘Effectiveness of Deworming Strategy in Reducing Anemia in Children: An Overview of Reviews’, Indian Journal of Community Medicine, 50(4), pp. 567–573. doi: https://doi.org/10.4103/ijcm.ijcm_628_23.
Degarege, A. et al. (2022) ‘Intestinal Helminth Infection, Anemia, Undernutrition and Academic Performance among School Children in Northwestern Ethiopia’, Microorganisms, 10(7), p. 1353. doi: https://doi.org/10.3390/microorganisms10071353.
Djuardi, Y. et al. (2021) ‘Soil-transmitted helminth infection, anemia, and malnutrition among preschool-age children in Nangapanda subdistrict, Indonesia’, PLOS Neglected Tropical Diseases. Edited by M. A. Gómez-Morales, 15(6), p. e0009506. doi: https://doi.org/10.1371/journal.pntd.0009506.
Girum, T. and Wasie, A. (2018) ‘The Effect of Deworming School Children on Anemia Prevalence: A Systematic Review and Meta-Analysis’, The Open Nursing Journal, 12(1), pp. 155–161. doi: https://doi.org/10.2174/1874434601812010155.
Husen, F. et al. (2022) ‘Increased Cholesterol Levels and Age in Housewives’, Jurnal Ilmiah Kesehatan Sandi Husada, 11(2 SE-Articles). doi: https://doi.org/10.35816/jiskh.v11i2.775.
Jolly, S. P. et al. (2023) ‘Water, sanitation and hygiene (WASH) practices and deworming improve nutritional status and anemia of unmarried adolescent girls in rural Bangladesh’, Journal of Health, Population and Nutrition, 42(1), p. 127. doi: https://doi.org/10.1186/s41043-023-00453-8.
Litaqia, W. and Cahya Mulat, T. (2025) ‘The impact of anemia on pregnant women on premature labor and low birth weight’, Jurnal Edukasi Ilmiah Kesehatan, 3(1), pp. 32–38. doi: https://doi.org/10.61099/junedik.v3i1.72.
Lo, N. C. et al. (2018) ‘Deworming in pre-school age children: A global empirical analysis of health outcomes’, PLOS Neglected Tropical Diseases. Edited by R. K. Prichard, 12(5), p. e0006500. doi: https://doi.org/10.1371/journal.pntd.0006500.
Molla, E. and Mamo, H. (2018) ‘Soil-transmitted helminth infections, anemia and undernutrition among schoolchildren in Yirgacheffee, South Ethiopia’, BMC Research Notes, 11(1), p. 585. doi: https://doi.org/10.1186/s13104-018-3679-9.
Moshi, C. C. et al. (2023) ‘Effect of Deworming on Health Outcomes among Children Aged 12–59 Months in Tanzania: A Multilevel Mixed Effects Analysis’, Journal of Nutrition and Metabolism. Edited by C. C. Wan, 2023, pp. 1–8. doi: https://doi.org/10.1155/2023/9529600.
Ngui, R. et al. (2012) ‘Association between Anaemia, Iron Deficiency Anaemia, Neglected Parasitic Infections and Socioeconomic Factors in Rural Children of West Malaysia’, PLoS Neglected Tropical Diseases. Edited by N. de Silva, 6(3), p. e1550. doi: https://doi.org/10.1371/journal.pntd.0001550.
Nuryati, A. (2024) ‘Meta Analysis: The Soil Transmitted Helminth Infection and It’s Correlation with Anemia in Children’, Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH), 11(2), pp. 33–41. doi: https://doi.org/10.23960/jbekh.v11i2.381.
Rennie, C. et al. (2021) ‘The Impact of Helminth Infection on the Incidence of Metabolic Syndrome: A Systematic Review and Meta-Analysis’, Frontiers in Endocrinology, 12, p. 728396. doi: https://doi.org/10.3389/fendo.2021.728396.
Salsabila, N. (2025) ‘Soil-Transmitted Helminths Infection and Macronutrient Intake among Stunted Toddlers in Jember District’, Media Gizi Indonesia, 20(1). doi: https://doi.org/10.20473/mgi.v20i1.74–80.
Shokeen, P., Pooja, K. and Neeraj, N. (2025) ‘From soil to stomach: How worms worsen nutritional deficits: A systematic review’, International journal of health sciences, 9(S1), pp. 557–566. doi: https://doi.org/10.53730/ijhs.v9nS1.15798.
Subahar, R. et al. (2020) ‘Intestinal Parasitic Infections and Hemoglobin Levels among Schoolchildren participating in a Deworming Program in Jakarta, Indonesia: A Cross-sectional Study’, Open Access Macedonian Journal of Medical Sciences, 8(E), pp. 589–594. doi: https://doi.org/10.3889/oamjms.2020.5153.
Toussaint Nguélé, A. et al. (2024) ‘Interplay Between Helminth Infections, Malnutrition, and Gut Microbiota in Children and Mothers from Pemba, Tanzania: Potential of Microbiota-Directed Interventions’, Nutrients, 16(23), p. 4023. doi: https://doi.org/10.3390/nu16234023.
Yeshi, K. et al. (2022) ‘Immunomodulatory and biological properties of helminth-derived small molecules: Potential applications in diagnostics and therapeutics’, Frontiers in Parasitology, 1. doi: https://doi.org/10.3389/fpara.2022.984152.
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